Certificate Reference
For continuity with the current catalog, this page links to laboratory documentation for a component or a closely related product. The linked certificate is a reference only and is not represented as the batch-specific COA for ACE-031.
Overview
ACE-031 is a soluble activin receptor type IIB (ActRIIB) fusion protein designed to bind myostatin and related activin-family ligands before they reach their native receptors. That makes it especially useful in models that examine how negative regulators of muscle growth shape muscle mass, tissue remodeling, and downstream metabolic signaling.
Research Reference: View identity reference
Research Focus
WHAT THIS FORMULA FEATURES
A ligand-trap approach to the myostatin/activin pathway rather than direct stimulation of muscle cells. Published human pharmacology work reported measurable changes in lean mass and thigh muscle volume after a single dose, while biomarker changes also pointed to effects on bone and fat metabolism.
EXPECTED RESEARCH READOUTS
Researchers commonly track lean-tissue or muscle-volume changes, myostatin/activin pathway biomarkers, muscle-cell growth signaling, and secondary bone- or fat-metabolism markers. These are research endpoints, not guaranteed outcomes for any individual experiment.
Research endpoints described above reflect published or model-based scientific observations and are not guaranteed outcomes. This product is strictly for research purposes only. Not approved for human or animal use.
Key Characteristics
MOLECULAR PROFILE
CAS: 1169766-01-1
Classification: Recombinant ActRIIB-Fc fusion protein
PHYSICAL PROPERTIES
Form: Lyophilized powder
Catalog strengths: 1 mg
Purity specification: ≥99% catalog specification; verify current batch COA
Storage: Store at −20°C (−4°F) for long-term storage or 4°C (39°F) for short-term storage; avoid repeated freeze-thaw cycles.
Testing: Batch documentation should be verified against the current lot before analytical use.
