Certificate of Analysis
Independent laboratory testing confirms purity and composition of this research peptide.
Endo Passed
Overview
AOD9604 is a synthetic peptide composed of 16 amino acids. It corresponds to residues 177 through 191 of its parent sequence, with a tyrosine residue at the N-terminus in place of the phenylalanine found at position 176. Its molecular formula is C78H123N23O23S2, its molecular weight is 1,815.1 g/mol, and its CAS number is 221231-10-3. The peptide contains an intramolecular disulfide bridge between two cysteine residues, which constrains its three-dimensional structure.
Because tyrosine differs from phenylalanine by a single hydroxyl group, AOD9604 and the unmodified 176-191 sequence are both 16-residue peptides that differ by exactly one oxygen atom — 1,815.1 g/mol versus 1,799.1 g/mol. That difference is not resolvable by HPLC purity analysis alone; mass-spectrometric identity confirmation is required to establish which of the two compounds is present in a given sample. AOD9604 was first synthesized in the 1990s and is supplied as a white to off-white lyophilized (freeze-dried) powder that is readily soluble in water.
This product is strictly for research purposes only. Not approved for human or animal use.
PubChem Reference: View compound profile on NIH PubChem
Key Characteristics
MOLECULAR PROFILE
Formula: C78H123N23O23S2
Weight: 1,815.1 g/mol
CAS: 221231-10-3
Origin: Residues 177-191 + N-terminal tyrosine
Size: 16 amino acids
Structure: Intramolecular disulfide bridge
PHYSICAL PROPERTIES
Form: White to off-white lyophilized powder
Solubility: Readily soluble in water; 0.6% acetic acid may be required
Stability: Stable under refrigerated storage
Storage: Keep refrigerated 36‑46 °F (2‑8 °C)
