Certificate Reference
For continuity with the current catalog, this page links to laboratory documentation for a component or a closely related product. The linked certificate is a reference only and is not represented as the batch-specific COA for SLU-PP-332.
Overview
SLU-PP-332 is a synthetic small-molecule agonist of the estrogen-related receptor family (ERRα/β/γ), with strongest activity reported at ERRα. It was developed as a chemical probe for exercise-responsive transcription, mitochondrial metabolism, and oxidative skeletal-muscle programming.
Research Reference: View compound profile on NIH PubChem
Research Focus
WHAT THIS FORMULA FEATURES
The defining feature is direct pharmacological activation of ERR signaling, a transcriptional network closely tied to mitochondrial biogenesis, oxidative metabolism, and exercise adaptation. Preclinical work has shown increased cellular respiration, a shift toward oxidative muscle-fiber features, and improved endurance in mice.
EXPECTED RESEARCH READOUTS
Typical endpoints include ERR target-gene expression, mitochondrial respiration, oxygen-consumption rate, oxidative phosphorylation markers, mitochondrial content, fatty-acid oxidation, skeletal-muscle fiber-type markers, and exercise-capacity endpoints in validated animal models.
Research endpoints described above reflect published or model-based scientific observations and are not guaranteed outcomes. This product is strictly for research purposes only. Not approved for human or animal use.
Key Characteristics
MOLECULAR PROFILE
Formula: C18H14N2O2
Weight: 290.3 g/mol
CAS: 303760-60-3
PubChem CID: 5338394
Classification: Small-molecule research compound
PHYSICAL PROPERTIES
Form: Lyophilized powder
Catalog strengths: 5 mg
Purity specification: ≥99% catalog specification; verify current batch COA
Storage: Store at −20°C (−4°F) for long-term storage or 4°C (39°F) for short-term storage; avoid repeated freeze-thaw cycles.
Testing: Batch documentation should be verified against the current lot before analytical use.
