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MOTS-c

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MOTS-c is a 16-amino-acid peptide with the molecular formula C 101 H 152 N 28 O 22 S 2 and a molecular weight of 2,174.6 g/mol (CAS 1627580-64-6). First described in 2015, MOTS-c is unusual because it is encoded by mitochondrial DNA rather than nuclear DNA. It belongs to a class called mitochondrial-derived peptides (MDPs) — short peptides encoded within the mitochondrial genome. Its sequence (MRWQEMGYIFYPRKLR) is found within the 12S rRNA gene of mitochondrial DNA, a region not previously known to produce peptides. MOTS-c is supplied as a white to off-white lyophilized powder, soluble in water, and should be stored refrigerated at 2-8 degrees C. This product is strictly for research purposes only.

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99%+ Purity Tests

Ships from Gilbert Arizona

USA Lab Tested

Proudly Made in the USA
USA manufactured, USA tested, ships from Gilbert, AZ
USA Manufactured
USA Lab Tested
Ships from Gilbert, AZ

✓ Third-Party Lab Tested

Certificate of Analysis

Independent laboratory testing confirms purity and composition of this research peptide.

Endo Passed

99.590% Purity
B2826061 Batch
July 2026 Date

View Certificate →

Overview

MOTS-c is a 16-amino-acid peptide with the molecular formula C 101 H 152 N 28 O 22 S 2 and a molecular weight of 2,174.6 g/mol. It was first described in 2015. What makes MOTS-c unusual among peptides is its origin: rather than being encoded by nuclear DNA (the DNA in the cell nucleus), it is encoded by the mitochondrial genome — the small, separate set of DNA found inside mitochondria, the energy-producing compartments of cells. Its CAS number is 1627580-64-6.

MOTS-c belongs to a class of molecules called mitochondrial-derived peptides (MDPs), which are short peptides encoded within mitochondrial DNA. Only a handful of MDPs have been identified so far, making this a relatively new category in peptide science. The peptide’s amino acid sequence — MRWQEMGYIFYPRKLR — is encoded within the 12S rRNA gene of mitochondrial DNA, a region previously thought not to produce proteins. MOTS-c is supplied as a white to off-white lyophilized powder, soluble in water, and should be stored refrigerated at 36-46 degrees F (2-8 degrees C).

This product is strictly for research purposes only.

PubChem Reference: View compound profile on NIH PubChem

This product is strictly for research purposes only. Not approved for human or animal use.

Key Characteristics

MOLECULAR PROFILE

Formula: C 101 H 152 N 28 O 22 S 2

Weight: 2174.6 g/mol

CAS: 1627580-64-6

Sequence: 16 amino acids

PHYSICAL PROPERTIES

Form: White to off-white lyophilized powder

Solubility: Water-soluble

Storage: Keep refrigerated 36–46 °F (2–8 °C)

Stability: Stable when properly stored

Additional information

Weight N/A
Dimensions N/A
Size

10mg, 40mg

SKU: OATH-MOTS-C Categories: , Tag:

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