Certificate Reference
For continuity with the current catalog, this page links to laboratory documentation for a component or a closely related product. The linked certificate is a reference only and is not represented as the batch-specific COA for Semaglutide.
Overview
Semaglutide is a long-acting GLP-1 receptor agonist and one of the best-characterized reference compounds for incretin and appetite-regulation research. GLP-1R activation links pancreatic hormone responses with central appetite circuits, gastric emptying, and broader metabolic signaling.
Research Reference: View compound profile on NIH PubChem
Research Focus
WHAT THIS FORMULA FEATURES
The molecule provides a durable GLP-1 signal with well-established effects on glucose-dependent insulin secretion, glucagon suppression, appetite and energy intake. Current mechanistic work also maps semaglutide action to specific GLP1R-expressing brain circuits and cAMP-dependent signaling.
EXPECTED RESEARCH READOUTS
Researchers commonly track GLP1R cAMP signaling, insulin and glucagon responses, glucose excursions, gastric-emptying or meal-response markers, food intake, appetite-related behavior, body weight and fat mass in appropriate models, and neuronal activation in GLP1R-expressing circuits.
Research endpoints described above reflect published or model-based scientific observations and are not guaranteed outcomes. This product is strictly for research purposes only. Not approved for human or animal use.
Key Characteristics
MOLECULAR PROFILE
Formula: C187H291N45O59
Weight: 4114 g/mol
CAS: 910463-68-2
PubChem CID: 56843331
Classification: 31-residue acylated GLP-1 analogue
PHYSICAL PROPERTIES
Form: Lyophilized powder
Catalog strengths: 5 mg | 10 mg | 15 mg | 20 mg | 30 mg | 50 mg
Purity specification: ≥99% catalog specification; verify current batch COA
Storage: Store at −20°C (−4°F) for long-term storage or 4°C (39°F) for short-term storage; avoid repeated freeze-thaw cycles.
Testing: Batch documentation should be verified against the current lot before analytical use.
