Certificate Reference
For continuity with the current catalog, this page links to laboratory documentation for a component or a closely related product. The linked certificate is a reference only and is not represented as the batch-specific COA for SS-31.
Overview
SS-31, also known as elamipretide, is a mitochondria-targeted tetrapeptide that accumulates at the inner mitochondrial membrane and interacts strongly with cardiolipin. This gives it a focused research role in mitochondrial membrane organization, electron transport, oxidative phosphorylation, and cellular energy recovery.
Research Reference: View compound profile on NIH PubChem
Research Focus
WHAT THIS FORMULA FEATURES
Cardiolipin interaction is the central feature. Published work shows that SS-31 can alter mitochondrial-membrane electrostatics, protect cardiolipin-dependent electron-transfer function, stabilize cristae architecture, and improve ATP-generating efficiency in experimental models of mitochondrial stress.
EXPECTED RESEARCH READOUTS
Common endpoints include mitochondrial oxygen consumption, ATP synthesis, membrane potential, cristae morphology, cardiolipin oxidation, cytochrome-c function, reactive oxygen species, calcium-stress handling, and recovery of bioenergetics after metabolic or ischemic challenge.
Research endpoints described above reflect published or model-based scientific observations and are not guaranteed outcomes. This product is strictly for research purposes only. Not approved for human or animal use.
Key Characteristics
MOLECULAR PROFILE
Formula: C32H49N9O5
Weight: 639.8 g/mol
CAS: 736992-21-5
PubChem CID: 11764719
Classification: Synthetic tetrapeptide / elamipretide
Sequence: D-Arg–2,6-dimethyl-Tyr–Lys–Phe-NH2
PHYSICAL PROPERTIES
Form: Lyophilized powder
Catalog strengths: 10 mg | 50 mg
Purity specification: ≥99% catalog specification; verify current batch COA
Storage: Store at −20°C (−4°F) for long-term storage or 4°C (39°F) for short-term storage; avoid repeated freeze-thaw cycles.
Testing: Batch documentation should be verified against the current lot before analytical use.
