Certificate Reference
For continuity with the current catalog, this page links to laboratory documentation for a component or a closely related product. The linked certificate is a reference only and is not represented as the batch-specific COA for Melanotan I.
Overview
Melanotan I is afamelanotide, a synthetic alpha-MSH analog and melanocortin-1 receptor (MC1R) agonist developed to produce a more stable and sustained melanocortin signal than native alpha-MSH. It is a well-characterized tool for pigmentation, melanocyte signaling, and photobiology research.
Research Reference: View compound profile on NIH PubChem
Research Focus
WHAT THIS FORMULA FEATURES
MC1R activation increases melanogenesis and has also been linked to antioxidant, DNA-repair, and inflammatory pathways in melanocytes and skin models. Human research with afamelanotide has demonstrated increased pigmentation, providing a clear pharmacodynamic reference for MC1R pathway activation.
EXPECTED RESEARCH READOUTS
Typical endpoints include cAMP signaling, tyrosinase activity, melanin content, eumelanin/pheomelanin balance, melanocyte gene expression, UV-response markers, oxidative stress, and DNA-repair signaling.
Research endpoints described above reflect published or model-based scientific observations and are not guaranteed outcomes. This product is strictly for research purposes only. Not approved for human or animal use.
Key Characteristics
MOLECULAR PROFILE
Formula: C78H111N21O19
Weight: 1646.8 g/mol
CAS: 75921-69-6
PubChem CID: 16197727
Classification: Synthetic 13-residue α-MSH analogue
PHYSICAL PROPERTIES
Form: Lyophilized powder
Catalog strengths: 10 mg
Purity specification: ≥99% catalog specification; verify current batch COA
Storage: Store at −20°C (−4°F) for long-term storage or 4°C (39°F) for short-term storage; avoid repeated freeze-thaw cycles.
Testing: Batch documentation should be verified against the current lot before analytical use.
