Certificate of Analysis
Independent laboratory testing confirms purity and composition of this research peptide.
Endo Passed
Overview
Semax is a synthetic heptapeptide — a chain of seven amino acids — with the sequence Met-Glu-His-Phe-Pro-Gly-Pro. It was first described in the late 1980s. Structurally, Semax is derived from a fragment of adrenocorticotropic hormone (ACTH), specifically the 4-10 segment, with an added Pro-Gly-Pro tripeptide tail that increases resistance to enzymatic degradation compared to the unmodified ACTH fragment.
The compound has a molecular formula of C37H51N9O10S (free acid form) and a molar mass of approximately 813.93 g/mol (826.92 g/mol as the acetate salt commonly supplied). It is water-soluble and supplied as a white to off-white lyophilized powder. Its CAS registry number is 80714-61-0. The Pro-Gly-Pro extension is a known structural motif used in peptide chemistry to resist cleavage by prolyl endopeptidases, distinguishing it structurally from the native ACTH(4-10) fragment.
This product is strictly for research purposes only. Not approved for human or animal use.
PubChem Reference: View compound profile on NIH PubChem
Key Characteristics
MOLECULAR PROFILE
Formula: C37H51N9O10S
Molar Mass: 813.93 g/mol
CAS: 80714-61-0
Sequence: Met-Glu-His-Phe-Pro-Gly-Pro
PHYSICAL PROPERTIES
Form: White to off-white lyophilized powder
Solubility: Water-soluble
Storage: Requires refrigeration after reconstitution
Stability: Stable in lyophilized form
