TB-500

Name: TB-500
SKU: OATH-TB-500
Availability: InStock

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TB-500 is the synthetic form of Thymosin Beta-4, a 43-amino-acid peptide first isolated from calf thymus tissue in the 1960s. It has the molecular formula C 212 H 350 N 56 O 78 S, a molecular weight of 4,963.4 g/mol, and is identified by CAS number 77591-33-4. The peptide is notable for containing a central actin-binding domain — a region structurally complementary to actin, a major structural protein found in biology. Thymosin Beta-4 is classified as a naturally occurring intracellular peptide and is one of the most abundant members of the beta-thymosin family. TB-500 is supplied as a white to off-white lyophilized powder, soluble in water, and should be stored frozen for long-term stability. This product is strictly for research purposes only.

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99%+ Purity Tests

Ships from Gilbert Arizona

USA Lab Tested

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USA manufactured, USA tested, ships from Gilbert, AZ

USA Manufactured

USA Lab Tested

Ships from Gilbert, AZ

Description
Additional information

✓ Third-Party Lab Tested

Certificate of Analysis

Independent laboratory testing confirms purity and composition of this research peptide.

Endo Passed

99.110% Purity
A2926031 Batch
August 2026 Date

View Certificate →

Overview

TB-500 is the synthetic form of Thymosin Beta-4, a 43-amino-acid peptide with the molecular formula C 212 H 350 N 56 O 78 S and a molecular weight of 4,963.4 g/mol. The naturally occurring version of this peptide was first isolated from calf thymus tissue in the 1960s during research into thymus gland extracts. TB-500 corresponds to the active region of the full Thymosin Beta-4 sequence.

Structurally, Thymosin Beta-4 is an unstructured, highly flexible peptide in solution, meaning it does not fold into a fixed three-dimensional shape the way many larger proteins do. It contains a central actin-binding domain — a stretch of amino acids structurally complementary to actin, one of the most common structural proteins in biology. The compound is identified by CAS number 77591-33-4 and appears as a white to off-white lyophilized powder that is soluble in water. It should be stored frozen for long-term stability.

This product is strictly for research purposes only.

PubChem Reference: View compound profile on NIH PubChem

This product is strictly for research purposes only. Not approved for human or animal use.