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VIP (Vasoactive Intestinal Peptide)

Price range: $60.00 through $327.99

VIP (Vasoactive Intestinal Peptide) is a 28-amino-acid neuropeptide and a member of the secretin–glucagon peptide superfamily, carrying a C-terminal amide. It has the molecular formula C147H237N43O43S, a molecular weight of approximately 3326.8 g/mol, and CAS number 40077-57-4. Its primary sequence is His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2. The peptide is a recognized ligand of the class B G-protein-coupled receptors VPAC1 and VPAC2. Supplied as a white to off-white lyophilized powder, soluble in water, stored refrigerated at 2–8 °C. This product is strictly for research purposes only.

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Overview

VIP (Vasoactive Intestinal Peptide) is a 28-amino-acid neuropeptide belonging to the secretin–glucagon peptide superfamily. It has the molecular formula C147H237N43O43S, a molecular weight of approximately 3326.8 g/mol, and CAS number 40077-57-4. First characterized from intestinal extracts, the peptide is widely distributed across the central and peripheral nervous systems and has been studied extensively in receptor-binding biochemistry.

VIP carries a C-terminal amide and signals through the class B G-protein-coupled receptors VPAC1 and VPAC2. Its full sequence is His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2. The conserved N-terminal histidine and the central helical region are the structural determinants of receptor recognition in in-vitro studies.

This product is strictly for research purposes only. Not approved for human or animal use.

PubChem Reference: View compound profile on NIH PubChem

This product is strictly for research purposes only. Not approved for human or animal use.

Key Characteristics

MOLECULAR PROFILE

Formula: C147H237N43O43S

Weight: 3326.8 g/mol

CAS: 40077-57-4

Structure: 28 amino acid C-terminally amidated peptide

PHYSICAL PROPERTIES

Form: White to off-white lyophilized powder

Solubility: Soluble in water

Purity: ≥98% (HPLC)

Storage: Keep refrigerated 36‑46 °F (2‑8 °C)

Additional information

Weight 0.08 lbs
Dimensions 0.87 × 1.18 × 0.87 in
Peptide

VIP

Strength

3mg, 5mg, 6mg, 10mg

CAS Number

37221-79-7

PubChem CID

53314964

Purity

≥99% (third-party HPLC and mass spectrometry verified)

Form

Lyophilized powder

Storage

Store at −20°C (−4°F) for long-term storage or 4°C (39°F) for short-term storage; avoid repeated freeze-thaw cycles.

Testing

Batch-specific COA included

Origin

Manufactured in the US

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